Evolence Collagen is The Newest Injectable Filler for Wrinkles and Folds: Promises of Longer Lasting Results But Can It Deliver?
EVOLENCE is a new, collagen-based, soft-tissue filler that quickly and effectively restores shape to facial wrinkles – with benefits lasting for at least 12 months. It is not FDA approved, but is currently available in Europe.
The long-lasting effect of EVOLENCE means that repeat injections may only be needed once a year or less, unlike some other biodegradeable fillers which often need repeating 2–3 times a year. Hyaluronic acid fillers such as Juvederm, Retylane and Perlane usually will require 2 treatments a year to maintain correction. I would be extremely cautious with this new product as most fillers when they first come to market claim they last twice as long as they actually do. For example when the first collagen was launched in the 1980s they said it would last 2 years when it actually lasted 2 months!
The company says that EVOLENCE achieves its long-lasting effects because it is specifically engineered to enhance stability and mimic the properties of natural collagen found in the skin. The filler is produced via the revolutionary Glymatrix™ technology. EVOLENCE is produced in the laboratory by polymerization of porcine (pig)collagen followed by glycation with natural sugar. BECAUSE IT COMES FROM A PIG IT WILL REQUIRE TWO ALLERGY TESTS PRIOR TO BEING ABLE TO USE IT FOR WRINKLE CORRECTION! Many patients also have objections to eating or putting any pig products in their body, so this would also be a potential problem for consumers.
A recent study published in the July 2007 issue of Plastic and Reconstructive Surgery noted EVOLENCE safety in 12 patients, but does not study how long it lasts. The jury is out in my mind until better studies are established in the US.
Posted by Dr Jacono at 10:30 PM